发表论文


代表论文

期刊论文

  • Yuan X, Glidle A, Yang Z and Wang B*, “Rapid enzymatic assays for fecal contamination in aquatic environment: challenges, advances and prospects”, Trends in Analytical Chemistry, 2024, 176, 117768. doi

  • Jiang G, Gao Y, Zhou N and Wang B*, “CRISPR-powered RNA sensing in vivo”, Trends in Biotechnology, 2024, 1–14. doi

  • Gao Y and Wang B*, “Toward predictable universal genetic circuit design”, Quantitative Biology, 2024, 1-5. doi

  • Buson F, Gao Y and Wang B*, “Genetic parts and enabling tools for biocircuit design”, ACS Synthetic Biology, 2024, 13(3), 697–713. doi

  • Gao Y, Wang L* and Wang B*, “Customizing cellular signal processing by synthetic multi-level regulatory circuits”, Nature Communications, 2023, 14, 8415. doi

  • Liu Y*, Liu W and Wang B*, “Engineering CRISPR guide RNAs for programmable RNA sensors”, Biochemical Society Transactions, 2023, 51(6), 2061–2070. doi

  • Gao Y#, Dong C#, Lian J* and Wang B*, “2nd symposium on engineering biology and BioFoundry”, Biotechnology Notes, 2023, 4, 100-103. doi

  • Wang B* and Tan C*, Special Issue “Synthetic biology for biosensing in health and environmental applications”, Biosensors, 2023, 13(10), 937. doi

  • Wang X, Zhou N and Wang B*, “Bacterial synthetic biology: tools for novel drug discovery”, Expert Opinion on Drug Discovery, 2023, 18(10), 1087-1097. doi

  • Fa-arun J, Huan Y, E Darmon and Wang B*, “Tail-engineered phage P2 enables delivery of antimicrobial phagemids into multiple gut pathogens”, ACS Synthetic Biology, 2023, 12, 2, 596–607 doi

  • Huan Y#, Torraca V#, Brown R#, Fa-arun J, Miles S, Oyarzun D, Mostowy S* and Wang B*, “P1 bacteriophage-enabled delivery of CRISPR-Cas9 antimicrobial activity against Shigella flexneri”, ACS Synthetic Biology, 2023, 12, 3, 709–721 doi

  • Huan Y, Brown R and Wang B*, “An adenine/thymidine-rich region is integral to RepL-mediated DNA replication”, Frontiers in Microbiology, 2023, 14, 1095671 doi

  • Liu Y, Pinto F, Wan X, Z Yang, Peng S, Li M, J Cooper, Xie Z, French C and Wang B*, “Reprogrammed tracrRNAs enable repurposing of RNAs as crRNAs and sequence-specific RNA biosensors”, Nature Communications, 2022, 13, 1937 doi pdf (Reported by Nature Research Bioengineering Blog, Regensis, BioArtMED, X‑MOL, biosyn‑met and LanHanBiotechnology among others)

  • Huan Y, Fa-arun J and Wang B*, “The role of O-antigen in P1 transduction of Shigella flexneri and Escherichia coli with its alternative S’ tail fibre”, Journal of Molecular Biology, 2022, 434(21), 167829 doi

  • Pan Y, Mao K, Hui Q, Wang B, Cooper J and Zhugen Yang*, “Paper-based devices for rapid diagnosis and wastewater surveillance”, Trends in Analytical Chemistry, 2022, 157, 116760 doi

  • Chen SY, Zhang Y, Li R, Wang B* and Ye BC*, “De novo design of the ArsR regulated Pars promoter enables a highly sensitive whole-cell biosensor for arsenic contamination”, Analytical Chemistry, 2022, 94(20), 7210‑7218 doi pdf

  • Li S, Xiao J, Sun T, Yu F, Zhang K, Feng Y, Xu C, Wang B and Cheng L, “Synthetic microbial consortia with programmable ecological interactions”, Methods in Ecology and Evolution, 2022, 13(7), 1608‑1621 doi pdf

  • Saltepe B, Wang L and Wang B*, “Synthetic biology enables field-deployable biosensors for water contaminants”, Trends in Analytical Chemistry, 2022, 146, 116507 doi pdf

  • Belkin S* and Wang B*, “Sense and sensibility: of synthetic biology and the redesign of bioreporter circuits”, Microbial Biotechnology, 2022, 15(1), 103-106 doi pdf

  • Ho T, Shao Y, Lu Z, Savilahti H, Menolascina F, Wang L, Dalchau N and Wang B*, “A systematic approach to inserting split inteins for Boolean logic gate engineering and basal activity reduction”, Nature Communications, 2021, 12, 2200 doi pdf (Reported by PhysOrg, Edinburgh BioSciences News, UoE SynthSys News and BioArt among others)

  • Lopreside A, Montali L, Wang B, Tassoni A, Ferri M, Calabretta M and Michelini E, “Orthogonal paper biosensor for mercury(II) contamination combining bioluminescence and colorimetric smartphone detection”, Biosensors and Bioelectronics, 2021, 194, 113569 doi pdf

  • Chen JX, Wang B, Thompson I, Huang EW, “Rational design and characterisation of nitric oxide biosensors in E. coli Nissle 1917 and mini SimCells”, ACS Synthetic Biology, 2021, 10(10), 2566–2578. doi pdf

  • Wan X, Saltepe B, Yu L and Wang B*, “Programming living sensors for environment, health and biomanufacturing”, Microbial Biotechnology, 2021, 14(6): 2334-2342. doi pdf

  • Liu Y, Pinto F, Wan X, Peng S, Li M, Xie Z, French C and Wang B*, “Reprogrammed tracrRNAs enable repurposing RNAs as crRNAs and detecting RNAs”, bioRxiv, 2021 doi

  • Yang S, Yang X, Wang B and Wang L, “Design and applications of fluorogenic nucleic acid paper-based biosensors”, Progress in Chemistry, 2021, 33(12), 2309-2315. doi pdf

  • Gale G, Wang B and McCormick A, “Evaluation and comparison of the efficiency of transcription terminators in different cyanobacterial species”, Frontiers in Microbiology, 2021, 11:624011 doi pdf

  • Wan X, Pinto F, Yu L and Wang B*, “Synthetic protein-binding DNA sponge as a tool to tune gene expression and mitigate protein toxicity”, Nature Communications, 2020, 11, 5961 doi pdf (Reported by Nature Research Bioengineering Blog, BioArt, zhihu‑Regensis and UoE SynthSys News among others)

  • Pinto F, Thornton E and Wang B*, “An expanded library of orthogonal split inteins enables modular multi-peptide assemblies”, Nature Communications, 2020, 11, 1529 doi pdf (Reported by Edinburgh BioSciences News, Nature Research Bioengineering Blog and BioArtReports among others)

  • Liu Y and Wang B*, “A novel eukaryote-like CRISPR activation tool in bacteria: features and capabilities”, BioEssays, 2020, 42(6), 1900252 doi pdf (Featured as Journal Front Cover Article)

  • Hicks M, Bachmann T and Wang B*, “Synthetic biology enables programmable cell-based biosensors”, ChemPhysChem, 2020, 21, 132–144 doi pdf (Featured as Journal Front Cover Article; ChemPhysChem Top Downloaded Paper)

  • Liu Y, Wan X and Wang B*, “Engineered CRISPRa enables programmable eukaryote-like gene activation in bacteria”, Nature Communications, 2019, 10, 3693 doi pdf (Reported by The National, The National Tribune, Drug Target Review, PhysOrg, Science Daily, BioArt, zhihu‑Regensis, Edinburgh University News and UoE SynthSys News among others)

  • Wan X, Volpetti F, Petrova E, French C, Maerkel S and Wang B*, “Cascaded amplifying circuits enable ultrasensitive cellular sensors for toxic metals”, Nature Chemical Biology, 2019, 15(5):540–548 doi pdf (Reported by Yahoo News, E&T Magazine, PhysOrg, Science Daily, Microbiologist, BioArt, Edinburgh Friends, Edinburgh University News and UoE BioSciences News among others)

  • Lopreside A, Wan X, Michelini E, Roda A and Wang B*, “Comprehensive profiling of diverse genetic reporters with application to whole-cell and cell-free biosensors”, Analytical Chemistry, 2019, 91, 15284−15292 doi pdf

  • Gale G, Schiavon A, Mills L, Wang B, Lea-Smith D and McCormick A, “Emerging species and genome editing tools: future prospects in cyanobacterial synthetic biology”, Microorganisms, 2019, 7(10):409 doi pdf

  • Gale G, Schiavon A, Puzorjov A, Wang B and McCormick A, “Genetic modification of cyanobacteria by conjugation using the modular cloning CyanoGate toolkit”, Journal of Visualized Experiments, 2019, (152), e60451 doi pdf

  • Vasudevan R, Gale G, Schiavon A, Puzorjov A, Malin J, Gillespie M, Vavitsas K, Zulkower V, Wang B, Howe C, Lea-Smith D and McCormick A, “CyanoGate: A modular cloning suite for engineering cyanobacteria based on the plant MoClo syntax”, Plant Physiology, 2019, 180(1):39-55 doi pdf

  • Liu Q, Schumacher J, Wan X, Lou C and Wang B*, “Orthogonality and burdens of heterologous AND gate gene circuits in E. coli”, ACS Synthetic Biology, 2018, 7(2):553-564 doi pdf (Featured in Edinburgh SynthSys Centre News; among Most Read Articles of ACS Synthetic Biology)

  • Hou J, Zeng W, Zong Y, Miao C, Wang B and Lou C, “Engineering the ultrasensitive transcription factors by fusing a modular oligomerization domain”, ACS Synthetic Biology, 2018, 7(5):1188–1194 doi pdf

  • Xiang Y, Dalchau N and Wang B*, “Scaling up genetic circuit design for cellular computing: advances and prospects”, Natural Computing, 2018, 17(4):833-853 doi pdf

  • Bernard E and Wang B*, “Synthetic cell-based sensors with programmed selectivity and sensitivity”, Methods in Molecular Biology, 2017, 1572:349-363 doi pdf

  • Brown R, Lengeling A and Wang B*, “Phage engineering: how advances in molecular biology and synthetic biology are being utilized to enhance the therapeutic potential of bacteriophages”, Quantitative Biology, 2017, 5(1):42-54 doi pdf

  • Bradley R, Buck M* and Wang B*, “Recognizing and engineering digital-like logic gates and switches in gene regulatory networks”, Current Opinion in Microbiology, 2016, 33:74–82 doi pdf

  • Bradley R, Buck M and Wang B*, “Tools and principles for microbial gene circuit engineering”, Journal of Molecular Biology, 2016, 428(5): 862-888 doi pdf

  • Bradley R and Wang B*, “Designer cell signal processing circuits for biotechnology”, New Biotechnology, 2015, 32(6): 635-643 doi pdf

  • Wang B*, Barahona M and Buck M, “Amplification of small molecule-inducible gene expression via tuning of intracellular receptor densities”, Nucleic Acids Research, 2015, 43(3): 1955-1964 doi pdf

  • Wang B*, Barahona M and Buck M, “Engineering modular and tunable genetic amplifiers for scaling transcriptional signals in cascaded gene networks”, Nucleic Acids Research, 2014, 42(14): 9484‑9492 doi pdf (Featured in Imperial College Science News)

  • Wang B* and Buck M, “Rapid engineering of versatile molecular logic gates using heterologous genetic transcriptional modules”, Chemical Communications, 2014, 50(79): 11642-11644 doi pdf (Featured as Journal Front Cover Article; Highlighted as a Hot ChemComm Article)

  • Lawton E, Jovanovic M, Joly N, Waite C, Wang B, Burrows P and Buck M, “Determination of the self-association residues within a Homomeric and a Heteromeric AAA + Enhancer Binding Protein”, Journal of Molecular Biology, 2014, 426(8): 1692-1710 doi pdf

  • Wang B*, Barahona M and Buck M, “A modular cell-based biosensor using engineered genetic logic circuits to detect and integrate multiple environmental signals”, Biosensors and Bioelectronics, 2013, 40(1): 368-376 doi pdf

  • Wang B*, Barahona M, Buck M and Schumacher J*, “Rewiring cell signalling through chimeric regulatory protein engineering”, Biochemical Society Transactions, 2013, 41(5): 1195-1200 doi pdf

  • Wang B* and Buck M*, “Customizing cell signalling using engineered genetic logic circuits”, Trends in Microbiology, 2012, 20(8): 376‑384 doi pdf

  • Beguerisse-Diaz M, Wang B, Desikan R and Barahona M, “Squeeze-and-breathe evolutionary Monte Carlo Optimisation with local search acceleration and its application to parameter fitting”, Journal of the Royal Society Interface, 2012, 9(73): 1925‑1933 doi pdf

  • Wang B, Kitney R*, Joly N and Buck M*, “Engineering modular and orthogonal genetic logic gates for robust digital-like synthetic biology”, Nature Communications, 2011, 2:508 doi pdf (Reported by Financial Times, EPSRC, European Commission, Electronics Weekly, Science Daily, UK Synthetic Biology Roadmap and Imperial College News among others)

会议论文

  • Ho T and Wang B*, “Intein-assisted Bisection Mapping (IBM)”, protocols.io, 2020 doi

  • Wang B*, Wan X, Billah M and Rahman A, “Arsenic: smartphone-friendly biosensor to tackle an insidious global threat”. Microbiologist, 2019, 20(3): 24-27 pdf

  • Wang B*, “Engineering customised cell signalling circuits and their biotechnological applications”. New Biotechnology, 2014, vol.31:S45 doi

  • Schumacher J, Wang B, Bonatto AC and Buck M, “Synthetic transcription factors allow regulon wide control and shifting the nitrogen/carbon balance in bacteria”, New Biotechnology, 2014, vol.31:S22 doi

  • Wang B, Kitney R, Buck M, Jovanovic M, Joly N and James E, “The design and construction of a set of modular synthetic BioLogic devices for programming cells”. World Congress on Medical Physics and Biomedical Engineering, Munich, IFMBE Proceedings, 2009, vol.25/8, pp.289-292 doi

  • Wang B, Bai J, Peng L and Li G, “EEG Recognition Based on Multiple Types of Information by Using Wavelet Packet Transform and Neural Networks”. Conf Proc IEEE Eng Med Biol Soc. 2005, vol.5:5377-80 doi

  • Wang L, Li G, Liu X, Wang B and Freeman WJ, “Study of A Chaotic Olfactory Neural Network Model and Its Applications on Pattern Classification”. Conf Proc IEEE Eng Med Biol Soc. 2005, vol.4:3640-43 doi

  • Ding Q, Li G, Wang B, Hu M and Li J, “Complexity and Topographic Analysis of EEG under Normal and Simulated High Altitude Acute Hypoxia Conditions”. Proceedings of International Conference on Neural Networks and Brain, 2005, vol.3:1526-29 doi

专著及章节

  • Wan X and Wang B*, “Engineering microbial sensor cell arrays to visualize environmental contaminants”, 2021, In: Avraham Rasooly and Houston Baker (eds.), Biosensors and Biodetection: Methods and Protocols, Springer; Methods in Molecular Biology.

  • Wan X, Ho T and Wang B*, “Engineering prokaryote synthetic biology biosensors”, 2019, In: Gérald Thouand (ed.) Handbook of Cell Biosensors, Springer, 37 pages. doi

  • Bernard E and Wang B*, “Synthetic cell-based sensors with programmed selectivity and sensitivity”, 2017, In: Avraham Rasooly and Ben Prickril (eds.), Biosensors and Biodetection: Methods and Protocols, Springer; Methods in Molecular Biology, 1572:349-363 doi

  • Wang B*, Engineering Genetic Logic Gates, Lambert Academic Publishing, ISBN: 978-3-659-27479-4, 2012, 208 pages. Amazon link, Publisher link

  • Wang B*, Design and Functional Assembly of Synthetic Biological Parts and Devices, PhD Dissertation, Imperial College London, 2011, 175 pages.