Nielsen, A. A. K. et al. Genetic circuit design automation. Science 352, aac7341 (2016).

In this publication, Nielsen and colleagues develop an authomated method for circuir design, which needs reliable predictability of promoter activity. For this purpose, they expand the previously characterized insulators (RiboJ) based on hammerhead rybozymes. These insulators cleave themselves upon transcription, standardizing the 5' region upstream to the ribosome binding site. Translation efficiencies are still dependant on the coding sequence used, but are independent of promoter context.

There is a patent related to this work, but it only claims property to the methods of circuit design and not the sequences.